PROUS SCIENCE SELECTS CHEMAXON TO EXTEND ONLINE KNOWLEDGE MINING

October 14th, 2005. Budapest, Hungary, and Barcelona, Spain: ChemAxon, a
software solutions provider for life sciences, today announced agreement
with Prous Science for the provision of ChemAxon’s JChem Cartridge
cheminformatics suite and Marvin, its Java-based structure editor and
viewer, for Prous Science web-based content products. The agreement
outlines the use of ChemAxon software initially within the Prous Science
Integrity® drug discovery and development portal.

Arriving in 2000, ChemAxon’s JChem suite has quickly become a leading
cheminformatics platform development toolkit enabling powerful searching
of mixed structural and nonstructural data. Based entirely in Java, the
suite is platform-independent, and for Marvin, the structure editor and
viewer element, means straightforward browser-based operation for online
interaction and delivery.

As a resource for empowering drug R&D activities and following the
progress of new chemical entities through the discovery and development
pipeline, Prous Science Integrity® reflects trends in pharmaceutical and
biotech research during the last 25 years.

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Integrity®’s more than
220,000 compounds offer comprehensive coverage of the most significant
discoveries in modern medicinal chemistry and biology as related to
drugs and therapeutics, along with a range of powerful tools to search,
filter and find relationships within the extensive content available.
Along with basic product information, Integrity® offers a wide array of
complementary data on experimental pharmacology, pharmacokinetics,
organic synthesis and targets, among other fields, allowing
investigators to originate new hypotheses in the discovery and
development of better and safer drugs. Since its introduction in 2001,
Integrity® has been adopted by major pharmaceutical and biotechnology
companies worldwide and by academic and health-care institutions to
drive knowledge creation, target mission-critical milestones, and
support strategic decisions in drug R&D.

The addition of the JChem suite functionality to the Integrity® portal,
now available, offers users new options for structure searching. The
integration of Marvin allows users to build complex, structure-based
queries directly from their browser window without the need for special
plugins or user native software.

Dr. Ferenc Csizmadia, CEO of ChemAxon, said, “We are happy to be working
with Prous Science, particularly in the area of knowledge-driven
discovery. It’s a good fit.” “The addition of the JChem suite provides
enhanced chemistry awareness within Integrity®, giving users an
extensive range of chemistry options directly from their desktop,” said
Dr. Josep Prous, Jr., Executive Vice President of Prous Science.

About ChemAxon
ChemAxon is a leader in providing Java based chemical software
development platforms for the biotechnology and pharmaceutical
industries. With core capabilities including structure visualization and
management, property prediction, virtual synthesis, screening and drug
design, ChemAxon focuses upon active interaction with users and core
portability to create powerful, cost effective cross platform solutions
and programming interfaces to power modern cheminformatics and chemical
communication.

For more information:
Contact: Alex Allardyce
Tel: +36 1 453 2658

About Prous Science
For more than 40 years, Prous Science has been a trusted source of
information on which science depends to discover safer and more
effective medicines. The company’s products have evolved through the
years from print journals to sophisticated electronic products
incorporating the latest advances in IT. More recently, Prous Science
has begun a series of research projects pushing the convergence of drug
discovery and knowledge mining. The results obtained by these
initiatives are excellent and demonstrate industry-leading performance.
For more information about Prous Science, visit www.prous.com

For more information:
Prous Science
P.O. Box 540 – 08080 Barcelona – Spain
Contact: Virginia Elizondo
Tel: +34 934 592 220 – Fax: +34 934 581 535

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